DNA testing

DNA Testing

A) DNA Telomere: Telomeres are sections of genetic material at the end of each chromosome whose primary function is to prevent chromosomal “fraying” when a cell replicates. As a cell ages, its telomeres become shorter. Eventually, the telomeres become too short to allow cell replication, the cell stops dividing and will ultimately die – a normal biological process. This test can determine the length of a patient’s telomeres in relation to the patient’s age. Then a regimen can be customized to slow the shortening of the DNA telomere as needed.

B) DetoxiGenomic Profile: This test evaluates SNPs associated with increased risk of impaired detoxification capacity especially when exposed to environmental toxins. It also identifies individuals potentially susceptible to adverse drug reactions.

Analytes Include:

COMT V158M CYP 1B1 N453S CYP1A1*2A
CYP1B1 L432V CYP2A6*2 CYP2C19*2
CYP2C19*3 CYP2C9*2 CYP2C9*3
CYP2D6*3 CYP1A1*2C CYP2E1*5A
CYP3A4*17 CYP3A4*1B CYP3A4*3
GSTM1 GSTP1 NAT 1 R187Q
NAT 1 R64W NAT 2 G286E NAT 2 I114T
NAT 2 K268R NAT 2 R197Q NAT 2 R64Q
SOD 1 A4V SOD 1 G93A SOD-2

C) EstroGenomic Profile: This test evaluates genetic variations, called single nucleotide polymorphisms (SNPs), in genes that modulate estrogen metabolism, coagulation, cardiovascular disease, and osteoporosis.

Analytes Include:

APOE COL1A1 COMT
CYP1A1 CYP1B1 Factor 2
Factor 5 GP3a GSTM1
GSTP1 IL-6 MTHFR
PAI-1 TNF – alpha VDR (vitamin D3 receptor)

D) ImmunoGenomic Profile: This test evaluates genetic variations in genes that modulate immune and inflammatory activity. These variations can affect balance between cell (Th-1) and humoral (Th-2) immunity, trigger potential defects in immune system defense, and stimulate mechanisms underlying chronic, overactive inflammatory responses.

Analytes Include:

IL-10 (interleukin -10) IL-13 (interleukin-13) IL-1B (interleukin- 1beta)
IL-4 (interleukin-4) IL-6 (interleukin-6) TNF-alpha

E) Neurogenomic Profile: This test evaluates single nucleotide polymorphisms (SNPs) in genes that modulate methylation, glutathione conjugation, oxidative protection and the potential to evaluate vascular oxidation.

Analytes Include:

COMT GSTM1 GSTP1 MTHFR SOD-2

F) OsteoGenomic Profile: This test evaluates genetic variations in genes that modulate bone formation (collagen synthesis), bone breakdown (resorption), and inflammation, including key regulatory mechanisms affecting calcium and Vitamin D3 metabolism.

Analyte list:

CALCR (calcitonin receptor) COL1A1 (Collagen 1) IL – 6 ( interleukin – 6)
TNF – alpha (Tumor necrosis factor) VDR ( vitamin D3 receptor)  
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