A) DNA Telomere: Telomeres are sections of genetic material at the end of each chromosome whose primary function is to prevent chromosomal “fraying” when a cell replicates. As a cell ages, its telomeres become shorter. Eventually, the telomeres become too short to allow cell replication, the cell stops dividing and will ultimately die – a normal biological process. This test can determine the length of a patient’s telomeres in relation to the patient’s age. Then a regimen can be customized to slow the shortening of the DNA telomere as needed.
B) DetoxiGenomic Profile: This test evaluates SNPs associated with increased risk of impaired detoxification capacity especially when exposed to environmental toxins. It also identifies individuals potentially susceptible to adverse drug reactions.
|COMT V158M||CYP 1B1 N453S||CYP1A1*2A|
|GSTM1||GSTP1||NAT 1 R187Q|
|NAT 1 R64W||NAT 2 G286E||NAT 2 I114T|
|NAT 2 K268R||NAT 2 R197Q||NAT 2 R64Q|
|SOD 1 A4V||SOD 1 G93A||SOD-2|
C) EstroGenomic Profile: This test evaluates genetic variations, called single nucleotide polymorphisms (SNPs), in genes that modulate estrogen metabolism, coagulation, cardiovascular disease, and osteoporosis.
|PAI-1||TNF – alpha||VDR (vitamin D3 receptor)|
D) ImmunoGenomic Profile: This test evaluates genetic variations in genes that modulate immune and inflammatory activity. These variations can affect balance between cell (Th-1) and humoral (Th-2) immunity, trigger potential defects in immune system defense, and stimulate mechanisms underlying chronic, overactive inflammatory responses.
|IL-10 (interleukin -10)||IL-13 (interleukin-13)||IL-1B (interleukin- 1beta)|
|IL-4 (interleukin-4)||IL-6 (interleukin-6)||TNF-alpha|
E) Neurogenomic Profile: This test evaluates single nucleotide polymorphisms (SNPs) in genes that modulate methylation, glutathione conjugation, oxidative protection and the potential to evaluate vascular oxidation.
F) OsteoGenomic Profile: This test evaluates genetic variations in genes that modulate bone formation (collagen synthesis), bone breakdown (resorption), and inflammation, including key regulatory mechanisms affecting calcium and Vitamin D3 metabolism.
|CALCR (calcitonin receptor)||COL1A1 (Collagen 1)||IL – 6 ( interleukin – 6)|
|TNF – alpha (Tumor necrosis factor)||VDR ( vitamin D3 receptor)|