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Astragalus: The King of Herbs

Astragalus: The King of Herbs

By Dr. Patrick Lovegrove Medically Reviewed by Lindsay Langley, BSN, RN, CHT
Posted Friday, March 15th, 2019
astragalus a herbal medicine known as king of herbs

Astragalus, also known as Milkvetch or huáng qí in Chinese, is an herbal medicine that has been used for hundreds of years. Its roots are used in traditional Chinese medicine. One of the few all-purpose herbs used, it is believed to support a wide array of biological functions. 

Even though Astragalus has over 2,000 species, only two are principally used in supplements – Astragalus mongholicus and Astragalus membranaceus. The main part of the plant utilized for medicinal purposes is its roots. It can be made into powders, capsules, and liquid extracts.

Pharmacological research has shown that the extract of astragalus herbal medicine (Astragalus membranaceus) can be quite beneficial to us. It increases telomerase activity and has immunoregulatory, antihyperglycemic, hypolipidemic, diuretic, antioxidant, and anti-inflammatory effects.

Immune System Support

Corroborated by various research studies, one of the major benefits of astragalus is its ability to support immune system function. According to a study published in Integrative Cancer Therapies, astragalus increases the production of white blood cells (notably T cells and macrophages), which play major roles in boosting the immune system.

In another study published in Alternative Medicine Review, intramuscular injections of astragalus for 3-4 months in patients with coxsackie-B viral myocarditis resulted in a significant increase in NK-cell activity. The patients consequently enjoyed an improvement in symptoms and general condition compared to pre-treatment levels.

In animal studies, astragalus has also been shown to help in killing viruses and bacteria. For instance, in a study that examined the effect and mechanism of Astragalus membranaceus on coxsackie B3 (CVB3) virus RNA in mice, it was observed that the copy numbers of CVB3-RNA, as well as the histologic necrotic sizes in myocardial tissues of AM. Treated infected mice were significantly smaller than that in infected normal saline-treated mice (P < 0.01, P < 0.05), respectively.” In conclusion, astragalus has proven itself beneficial for the immune system.

Blood Sugar Health

In addition to supporting the immune system, astragalus has also been shown to help maintain healthy blood sugar levels. It is excellent herbal medicine. One study showed that taking 40-60g of astragalus on daily basis for four months can potentially improve post-meal and post-fasting blood sugar levels in individuals with Type 2 diabetes. 

Similarly, in an animal study published in the Journal of Ethnopharmacology, where the researchers examined whether treatment with the astragalus polysaccharide (from Astragalus membranaceus) improves insulin sensitivity in insulin-resistant mice. They observed that the astragalus treatment ameliorated hyperglycemia and insulin resistance. Interestingly, astragalus is the most frequently used herb used in traditional Chinese medicine for the maintenance of blood sugar levels.

Heart Health Support

The profound benefits of astragalus also extend to the heart. It is believed that the astragalus can improve heart function by widening the blood vessels and increasing the amount of blood pumped from the heart. In one study, which examined the effects of astragalus on cardiac function, 2.25g of astragalus was administered twice daily to patients suffering from heart failure over a period of two weeks, alongside conventional treatment. At the end of the study, it was observed that patients who received the astragalus enjoyed a higher improvement in health function in comparison with those who received conventional treatment only.

In a similar study where cardiovascular patients were given 60g of astragalus per day by IV, alongside conventional treatment, it was also observed that the patients enjoyed more significant improvements compared to those receiving only conventional treatments.

Optimal Kidney Function

Astragalus is also believed to aid kidney function by improving blood flow, as well as markers of kidney function such as protein content in the urine. For instance, astragalus has been shown to improve proteinuria – a condition characterized by abnormal amounts of protein in the urine. In a study that examined the efficacy of Astragalus in the treatment of chronic kidney disease, it was observed that “astragalus significantly decreased 24-hour proteinuria at end of treatment.”

Astragalus may also help improve the bacterial flora in individuals with reduced kidney functions. According to a study published in the Cochrane Database of Systematic Reviews, 7.5-15g of astragalus taken daily for 3-6 months caused a 38% reduction in the risk of infection in patients with nephrotic syndrome with no serious adverse events reported. Although more research is still required. The existing evidence certainly reveals that astragalus is really good news for kidney function and by extension, overall health.

Considered as the herb of longevity, this herb has certainly stood the test of time in proving itself as king of herbs.

About the author

Dr. Patrick Lovegrove

Dr. Patrick Lovegrove is board certified by the American Board of Family Physicians. He was born in Staunton, Virginia, and graduated from the University of Virginia where he majored in Biology. He received a Medical School Scholarship from the United States Air Force. A graduate of Nova Southeastern College of Osteopathic Medicine, his over 20 years of clinical experience includes Family Practice, Anti-aging, Holistic Internal Medicine, Pain Management, Aerospace, Sports, and Emergency Medicine. He believes that holistic medicine should be integrated with conventional medicine in a scientifically based model to achieve the best results for patients.